3D Nanofiber Cell Culture Scaffolds for Tunable Microenvironments

USF nanofilm scaffolds provide defined, reproducible nanofiber architecture in familiar cell culture formats. Explore data across cell types.

See How Cells Respond to Nanofiber Architecture

Cell Organization & Morphology 

See how nanofiber architecture influences cell morphology, alignment, elongation, and spatial organization across different cell models.


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Neuronal Models

Explore how nanofiber density and patterning influence neuronal patterning, alignment, and axonal organization in iPSC-derived human cortical neurons.

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​Stem Cell Fate & Differentiation

Explore how nanofiber biophysical cues influence cellular differentiation using existing protocols.

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Drug Response

Compare drug response curves from standard 2D plates and USF nanofiber cell culture scaffolds.


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Interested in exploring USF nanofiber scaffolds with your cell model?

Connect with our team to discuss how defined nanofiber architecture could support your cell culture application.

How USF Nanofilms Compare With Common 3D Cell Culture Approaches


USF nanofilm scaffolds are designed to combine defined nanofiber architecture with tunability, reproducibility, optical access, and compatibility with standard cell culture workflows. 

Screen Six Nanofiber Conditions in One 24-Well Plate

Not every cell model responds to the same nanofiber configuration. USF Tuning Plates provide six defined nanofiber conditions in a familiar 24-well format, helping researchers compare how physical architecture relates to the readouts that matter for their application.


Each of the six columns provides a distinct nanofiber density or pattern. The four rows can be used for different coatings or experimental conditions, allowing you to compare cellular behavior across microenvironments and identify the optimal fiber density for your cells and application.

* Diagram intended for illustrative purposes only.

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Interested in exploring USF nanofiber scaffolds with your cell model?